Advances in pathogenesis and molecular biology of endometrial carcinoma]

Cancer research has evolved at a phenomenal pace over the past two decades. Advances in genetics and molecular biology expand the knowledge gathered in the subject. Endometrial carcinoma is a common invasive malignancy in the female genital tract and presents an important diagnostic and treatment challenge. The research aims to develop new molecular tools for early diagnosis and optimal treatment of the disease and its precursors. An updated review of the molecular and genetic research is presented with correlation to the pathological and clinical characteristics of the tumor.