Study on Chemical Constituents in Tuber of Harpagophytum procumbens D.C.

OBJECTIVE To investigate chemical components in the tuber of Harpagophytum procumbens D.C. METHODS The chemical components were isolated by column chromatography methods,and the structures were elucidated by spectral evidence.RESULTS Nine compounds were isolated.Compound 1～5 were phenylpropanoid glycosides and 6 was a triterpenoid saponin,then each was identified as martynoside(1),6-acetyl acteoside(2),β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-glucopyranoside(3),acteoside (4)+ isocteoside(5),7α,23-dihydroxytormentic acid ester glucoside(6),ethyl ferulate(7),pentacosanoic acid(8) and β-daucosterol(9),respectively.CONCLUSION Compound 1,6,7 and 8 are isolated from this plant for the first time.