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SD大鼠坐骨神经对腺样囊性癌细胞系ACC-M体外增殖能力的影响

Xiang-ming YANG,Mo-yi SUN,Bo-lei CAI,Wen-rong JIA,Jian-hu LI

Chinese Journal of Aesthetic Medicine（2010）

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Abstract
目的:研究SD大鼠坐骨神经对腺样囊性癌ACC-M细胞体外增殖能力的影响.方法:将人腺样囊性癌细胞系(ACC-M)分别与条件培养液和坐骨神经培养液共培养24、48、72h.应用MTT比色法研究SD大鼠坐骨神经对腺样囊性癌ACC-M细胞体外增殖能力的影响.结果:坐骨神经培养液对ACC-M作用48和72h后,ACC-M细胞的增殖明显高于其它组别,而共培养液则对ACC-M细胞的增殖没有明显影响.结论:SD大鼠坐骨神经培养液作用于腺样囊性癌细胞,能有效促进腺样囊性癌细胞的增殖,这可能是腺样囊性癌嗜神经侵袭的基础.
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Key words
perineural invasion,sciatic nerve,proliferation,adenoid cystic carcinoma(ACC)
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