Studies on compounds of cancer chemoprevention: synthesis of some amides]
Yao xue xue bao = Acta pharmaceutica Sinica（1994）
Abstract
In search for cancer chemoprevention agents, seven new amide compounds have been synthesized. The structures have been determined based on spectral and chemical data. N-4-(ethoxycarbophenyl)-alpha-naphthamide and N-4-(ethoxycarbophenyl)-beta-naphthamide were shown to be 81% and 79% effective, respectively, for inducing different in HL-60 human promyelocytic leukemia cells at the concentration of 10(-5) mol/L in NBT tests.
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Antitumor Activity
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