比亚芬预防放射性皮肤损伤的疗效观察
Chinese Journal of Radiation Oncology(2004)
Abstract
目的观察比亚芬乳膏预防急性放射性皮肤损伤的临床疗效.方法将104例需要放射治疗的患者随机分为2个组,56例在第1次放射治疗后给予比亚芬涂抹为用药组,48例只做常规放射治疗宣教和健康教育为对照组.结果皮肤反应发生率对照组和用药组分别为93.8%、30.4%.轻度放射反应(1+2级)对照组为66.7%(32/48),用药组为28.6%(16/56).皮肤反应发生剂量对照组91.1%(41/45)出现于照射40 Gy以前,用药组为29.4%(5/17).结论比亚芬能有效地预防放射性皮炎的发生,对患者能减轻痛苦、提高生活质量、保证放射治疗的顺利进行.
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Key words
biafine cream,dermal injury,clinical effect,irradiation-induced
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