颅内肿瘤瘤周水肿相关研究进展

Medical Recapitulate(2012)

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Abstract
颅内肿瘤瘤周水肿指脑肿瘤周围脑实质内水分的异常增多。瘤周水肿的发生机制复杂,国内外学者研究认为可能与水通道蛋白4、血管内皮生长因子受体表达等因素有关;瘤周水肿的诊断已经从CT、MRI发展到DWI、CTP、MTP,甚至可用1H-MRS通过瘤周水肿来判断肿瘤的性质;瘤周水肿除传统的脱水治疗外,水通道蛋白4激动剂或拮抗剂,血管内皮生长因子受体拮抗剂也有很好的治疗潜力。
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Key words
Peritumoral edema,AQP-4,VEGF,Imaging,Treatment,Intracranial tumors
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