Unilateral or bilateral irradiation in cervical lymph node metastases of unknown primary? A retrospective cohort study.

Carole Pflumio,Idriss Troussier, Xu Shan Sun,Julia Salleron,Claire Petit,Matthieu Caubet,Arnaud Beddok,Valentin Calugaru,Stéphanie Servagi-Vernat,Joël Castelli,Jessica Miroir,Marco Krengli,Paul Giraud,Edouard Romano,Jonathan Khalifa,Mélanie Doré,Nicolas Blanchard,Alexandre Coutte,Charles Dupin,Shakeel Sumodhee,Yoann Pointreau,Samir Patel, Amel Rehailia-Blanchard, Ludivine Catteau,René-Jean Bensadoun,Yungan Tao,Vincent Roth,Lionnel Geoffrois,Jean-Christophe Faivre, Juliette Thariat

European Journal of Cancer（2019）

Cited 12|Views13

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Abstract

•Our study suggests that bilateral neck irradiation might yield better outcomes.•Mucosal irradiation yielded better local control.•Severe toxicities with bilateral 3D irradiation could be reduced with IMRT.•Unilateral elective irradiation cannot yet be considered the standard treatment.

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Key words

Neoplasms,Unknown primary,Head and neck neoplasms,Radiotherapy,Neck dissection,Chemotherapy

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