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原发性肝癌靶体积对立体定向放射治疗计划设计的影响分析

Chinese Journal of Medical Physics(2011)

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Abstract
目的:分析原发性肝癌靶体积对γ射线立体定向放射治疗计划设计的影响.方法:2008.05~2010.03采用γ射线立体定向放射治疗139例原发性肝癌患者,共146个靶区,以计划靶区体积(Vptv)大小分成三组:A组41个,Vptv<150cm2;B组77个,150 cm3≤Vptv<300 cm3;C组28个,Vptv≥300 cm2.比较分析各组立体定向放射治疗计划.结果:146个靶区均50%~90%等剂量线覆盖.靶体积越小,覆盖靶区的等剂量线越高;A组等中心数最少,C组最多,B组次之;A组剂量均匀性最好,B、C无明显差别.结论:靶体积大小影响原发性肝癌立体定向放射治疗计划设计,靶体积越小,所需的等中心数更少,靶区均匀性越好,覆盖靶区的等剂量线越高.
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Key words
liver cancer.,treatment plan,stereotactic radiotherapy
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