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胃肠及胃肠外间质瘤临床病理及免疫组化观察

Practical Journal of Clinical Medicine(2006)

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Abstract
目的探讨胃肠间质瘤(G IST)及胃肠外间质瘤的病理诊断和免疫组化特点,为其诊断、鉴别诊断、预后提供依据。方法对39例胃肠及胃肠外间质瘤进行形态学观察分析,用免疫组化(S-P)法检测CD117、CD34、V im、SMA及S-100蛋白。结果39例胃肠及胃肠外间质瘤主要由梭形细胞和上皮样细胞构成,其中38例CD117阳性,32例CD34阳性。结论胃肠间质瘤具有多向分化性,HE形态类似,CD117、CD34免疫标记阳性对诊断有意义。
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Key words
CD34,Gastrointestinal stromal tumor,Immunohistochemistry,CD117
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