Levels of soluble LR11/SorLA are highly increased in the bile of patients with biliary tract and pancreatic cancers.

Kensuke Terai,Meizi Jiang,Wataru Tokuyama,Takeyoshi Murano,Nobuo Takada,Kengo Fujimura,Hiroyuki Ebinuma,Toshihiko Kishimoto,Nobuyuki Hiruta,Wolfgang J Schneider,Hideaki Bujo

Clinica Chimica Acta（2016）

引用 17|浏览9

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摘要

•Bile sLR11 is increased in patients with cancer of biliary tract (BTC) or pancreas (PC).•LR11 protein is highly expressed in BTC and PC cells.•LR11 mRNA levels increase in cultured cholangiocarcinoma and PC cells under hypoxic conditions.•Bile sLR11 levels may be a potential novel biomarker in patients with BTC or PC.

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关键词

Biliary tract cancer,Pancreatic cancer,Bile,Soluble LR11

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