Safety and efficacy of cell-based therapy on critical limb ischemia: A meta-analysis.
Cytotherapy(2016)
Abstract
•We systematically reviewed stem cell-based therapy on critical limb ischemia.•We conducted trial sequential analysis to calculate the required sample size in all-cause mortality.•The dose-response meta-analysis was applied to show the relationship between amount of stem cell and therapeutic effect.
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Key words
Cell-based therapy,Clinical trial,Critical limb ischemia,Meta-analysis,Peripheral arterial disease
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