The potential effect of Bruton's tyrosine kinase in refractory periapical periodontitis.
Biomedicine & Pharmacotherapy（2019）
Abstract
•BTK expression increased in refractory periapical periodontitis.•BTK played an important role in the bone destruction of refractory periapical periodontitis.•BTK could promote the proliferation of osteoclasts in the E. faecalis LTA-mediated inflammatory microenvironment.
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Key words
BTK,Bone absorption,E. faecalis,Refractory periapical periodontitis,Osteoclast
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