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Polarization of M1 tumor associated macrophage promoted by the activation of TLR3 signal pathway.

Bo Liu,Xia Wang,Tai-Zhong Chen,Guang-Liang Li,Chang-Chun Tan,Yong Chen, Shao-Qiang Duan

Asian Pacific Journal of Tropical Medicine（2016）

Cited 17|Views3
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Abstract
The Poly-ICLC can activate the TLR3 downstream signaling pathway to induce a M1 polarization of tumor associated macrophage, thereby inhibiting the tumor growth.
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Key words
Tumor-associated macrophage,TLR3,Poly-ICLC,M1
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