Interaction of Lasioglossin III with CCRF-CEM Cells

Antimicrobial peptides isolated recently from the venom reservoirs of wild bees are active not only against bacteria and fungi, but also selectively lyze some cancer cell lines. At the same time they have very low hemolytic activity and concentrations required to lyze control normal cell lines are much higher. Here we describe the time course of the effect of lasioglossin III (LL-III) on CCRF-CEM cells alone and in the mixture with human red blood cells using flow cytometry.