Dendritic Cells Exposed to Triiodothyronine Deliver Pro-Inflammatory Signals and Amplify IL-17-Driven Immune Responses.

Vanina Alejandra Alamino,María Del Mar Montesinos,María Florencia Soler, Lucila Giusiano, Nicolás Gigena,Laura Fozzatti,Sebastián Matías Maller,Santiago Patricio Méndez-Huergo,Gabriel Adrián Rabinovich,Claudia Gabriella Pellizas

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2019）

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摘要

These results emphasize the relevance of T3 as an additional immune-endocrine checkpoint and a novel therapeutic target to modulate IL-17-mediated pro-inflammatory responses.

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关键词

Adaptive immunity,Dendritic cells,Pro-inflammatory signals,Th17,Triiodothyronine,γδ-T cells

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