The Hidden Economy of HSC Transplantation Is Inconsistent with Prohibiting the Compensation of HSC Donors

I. Background 219 A. HSCs and HSC Transplants 219 1. Hematopoietic (Blood Forming) Stem Cells ...... 219 2. The Role of Histocompatibility in HSC Transplants 220 3. Sources of HSCs for Transplant 223 B. History of HSC Transplantation 228 C. The Administrative System for Unrelated HSC Donations in the United States 235 II. Regulation of the Sale of HSCs 237 A. Federal 238 1. National Organ Transplant Act (NOTA) 238 2. U.S. Food and Drug Administration (FDA) ...... 241 B. State Laws 243 C. Accrediting Organizations and Registry Requirements 245 III. Donors Should Be Permitted to Receive Compensation in Exchange for HSCs, Regardless of the Source of the HSCs 248 A. Permitting HSC Donors to Be Compensated Will Not Change the Status of HSCs as Commodities... 249 B. Precluding Compensation for HSC Donation to Prevent Donor Profiting Is Inconsistent with the Hidden Economy of HSC Donation Where All Parties Involved in HSC Transplantation,