Social and functional outcomes with two doses of aripiprazole lauroxil vs placebo in patients with schizophrenia: a post-hoc analysis of a 12-week phase 3 efficacy study.

Psychiatry Research(2019)

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摘要
•Social functioning difficulties are a major problem for persons with schizophrenia.•Functional challenges are relatively unresponsive to acute antipsychotic treatment.•Aripiprazole lauroxil every 4 weeks for 12 weeks significantly improved social functioning vs placebo.•Improving social functioning is a suitable target for acutely symptomatic patients.
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关键词
Long-acting antipsychotic,Negative symptoms,PANSS Prosocial subscale,Personal and Social Performance scale
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