Abstract WMP14: Prognosis of Different Infarction Patterns in Single or Multiple Acute Infarction After Minor Stroke

Objective: To investigate whether different infarction patterns of single acute infarction (SAI) and multiple acute infarctions (MAIs) respectively have different risk of stroke recurrence after minor stroke. Methods: We derived data from the imaging subgroup of the Clopidogrel in High-risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial. Minor stroke were categorized into SAI and MAIs according to infarction patterns in diffusion weighted imaging. SAI were classified as 1.Cortical lesion; 2.Subcortical lesion with diameteru003e15mm; 3.Subcortical lesion with diameter≤15mm; 4.Corticosubcortical lesion. MAIs were classified as 1.Unilateral anterior circulation; 2.Posterior circulation; 3.Multiple circulations; 4.Border-zone territories. The primary outcome was stroke recurrence at one-year follow-up. Results: A total of 834 patients with minor stroke from 45 of 114 participating centers of the trial undergoing baseline MRI were included in this imaging subgroup. SAI was observed in 553 a...