GW29-e0367 PTEN Induced Putative Kinase 1 (PINK1) Regulates Mitophagy to Alleviate Angiotensin II-Induced Cardiac Injury

Wenjun Xiong,Jiaying Li,Zhengliang Peng,Zhuang Ma,Xiangkun Xie,Hanlin Li,Zhen Se,Wenyan Lai,Qiong Zhan,Qingchun Zeng,Hao Ren,Dingli Xu

Journal of the American College of Cardiology（2018）

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摘要

Angiotensin Ⅱ (Ang Ⅱ)-induced cardiac injury can result in elevated oxidative stress and decreased mitochondrial quality. Meanwhile, PTEN induced putative kinase 1 (PINK1) participate in mitochondrial quality control. However, the mechanism of PINK1 in Ang Ⅱ-induced cardiac injury remain

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关键词

kinase,mitophagy,ii-induced

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