Abstract 13228: SUMO2 Induces Cardiac Hypertrophy in Vivo and in Vitro, Independent of Sumoylation

Alexander Bernt,Ashraf Yusuf Rangrez,Matthias Eden,Claudia Rohr,Sylvia Katz,Andreas Jungmann,Tatjana Williams,Oliver Ritter,Oliver Müller,Hugo A. Katus,Derk Frank,Norbert Frey

Circulation（2016）

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摘要

Introduction: The calcineurin (Cn)-NFAT signaling axis is a pivotal pathway in cardiac physiology and pathophysiology including remodeling and pathological hypertrophy. Methods and results: We have...

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