Abstract 21400: Morphological Analysis of Transcranial Doppler Waveforms for Large Vessel Occlusion Diagnosis

Introduction: Underlying cardiac conditions such as atrial fibrillation (AF) and cardiac procedures such as transcatheter aortic valve replacement (TAVR) and coronary artery bypass grafting (CABG) have been shown to lead to large vessel occlusions (LVO) causing significant mortality and morbidity and improved pre, peri, post procedural methods for diagnosis are needed. Transcranial Doppler (TCD) is a rapid, inexpensive and portable tool for assessment of cerebral blood flow velocity (CBFV) that is used clinically and has been shown to have potential as a diagnostic aid for LVO. The utilization of the morphological information from the TCD waveform has shown to provide additional diagnostic capabilities in many neurological conditions and may improve LVO detection over traditional TCD metrics of mean velocity and pulsatility index. However, traditional TCD techniques suffer from a number of limitations including operator skill level and variability due to depth and location selection. Hypothesis: The morph...