Efficacy analysis of using enhanced recovery after surgery in perioperative period of radical surgery for cholangiocarcinoma

Objective: To investigate the safety and efficacy of using enhanced recovery after surgery (ERAS) in perioperative period of patients undergoing radical surgery for cholangiocarcinoma. Methods: The clinical data of a total of 149 patients undergoing radical surgery for cholangiocarcinoma from April 2013 to April 2017 were collected. Of the patients, 73 cases received ERAS perioperative management (ERAS group), and 76 cases received traditional perioperative management (traditional group). The surgical procedures in either group included partial hepatectomy with choledochojejunostomy, choledochojejunostomy and pancreaticoduodenectomy. The main clinical variables were compared between the two whole groups of patients or between subgroups of patients with same surgical procedure. Results: The preoperative general data showed no statistical difference either between the two whole groups of patients or between subgroups of patients with same surgical procedure (all P>0.05). After surgery, the comparisons either between the two whole groups of patients or between subgroups of patients with same surgical procedure showed that the liver function parameters and/or recovery parameters in ERAS group were more or less significantly superior to those in traditional group (all P< 0.05). No significant difference was noted in incidence of complications between the two whole groups of patients or between subgroups of patients with same surgical procedure (all P>0.05). Conclusion: Using ERAS in perioperative period in the perioperative period of patients undergoing radical surgery for cholangiocarcinoma is safe and effective, which is helpful to accelerate the postoperative recovery of the patients.