Case Report Plasmablastic Lymphoma

Plasmablastic lymphoma (PBL) is a rare and aggressive subtype of non-Hodgkin lymphoma that commonly occurs in human immunodeficiency virus (HIV)–positive individuals and affects oral sites. The aim of this work was to report a case of a 57-year-old female patient diagnosed with HIV infection, presenting with a purplish exophytic lesion, which was bleeding, painful, friable, located in the maxilla, and affecting the alveolar ridge of teeth #23 to #27, hard palate, and vestibule. Panoramic radiography was performed. Initially, Kaposi sarcoma was suspected. However, after incisional biopsy and positive immunohistochemical reactions for Ki-67 (high expression), LCA, plasma cell, CD138, and EBER and negative reaction for CD20 and CD34, the diagnosis of PBL was established. The patient's health status deteriorated rapidly, and shortly after the receiving the results of the analyses, she died before initiation of cancer treatment.