Development And Temporal Validation Of A Practical Prognostic Scoring System (Oncogeriatric Index -Ogi) Based On The Comprehensive Geriatric Assessment To Predict Early Death In Elderly Cancer Patients: A 892 Patients Cohort Study.

JOURNAL OF CLINICAL ONCOLOGY(2018)

引用 0|浏览7
暂无评分
摘要
10049Background: Recognizing prognostic factors is important when evaluating elderly people with cancer to decide the appropriate treatment. The Oncogeriatric Index (OGI) was developed to predict early death (in 6 months) among elderly people with cancer, based on the Karnofsky Performance Status Scale, the Mini Nutritional Assessment and the Charlson Comorbidity Index. OBJECTIVES: To temporarily validate the OGI.Methods: We used a prospective cohort of cancer patients aged 60 or + years for GA n 605 (2015-2017) [training set]; 2016–2017: n 291 [validation set]) was performed during a six-month follow-up. Epidemiologic data and CGA (using 12 scales) before oncologic treatment were collected. The outcome was ED (within first 180 days). Cox’s proportional hazards model was used for the selection of prognostic factors. A prognostic score, the Onco Geriatric Index (OGI), was constituted of the number of abnormal CGA scales. Overall survival was estimated using the Kaplan–Meier method, and survival curves were...
更多
查看译文
关键词
elderly cancer patients,comprehensive oncogeriatric assessment,practical prognostic scoring system,patients cohort study
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要