Core Biopsies from Prostate Cancer Patients in Active Surveillance Protocols Harbor PTEN and MYC Alterations

Paolo Gandellini,Nicola Casiraghi,Tiziana Rancati,Matteo Benelli,Valentina Doldi,Alessandro Romanel,Maurizio Colecchia,Cristina Marenghi,Riccardo Valdagni,Francesca Demichelis,Nadia Zaffaroni

European Urology Oncology（2019）

引用 3|浏览21

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摘要

The presence of adverse outcome-related genomic lesions, such as PTEN deletion and MYC amplification, in GPS=3+3 diagnostic core biopsies of prostate cancer patients could be considered for a more precise/earlier selection of patients not suitable for active surveillance.

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关键词

Active surveillance,Whole-exome sequencing,Biopsy

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