An efficient synthesis of indoles via a CuMgAl-LDH-catalyzed cyclization of 2-alkynylsulfonanilides

Sheng-Yan Zhang, Shan-Gang Sun,Yu-Shuang Guo,Xiao-Fan Lu,Dian-Shun Guo

Tetrahedron Letters（2018）

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摘要

•A green synthesis of indoles via CuMgAl-LDH-catalyzed cyclization is reported.•CuMgAl-LDH catalyst features facile preparation and unique dual activation.•This method shows broad substrate scope, mild conditions and high efficiency.

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关键词

Indole,2-Alkynylsulfonanilide,Cyclization reaction,CuMgAl-LDH catalyst,Hirshfeld surface analysis

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