Cardiac Arrest and Seizure Following Cannabis Overdose and Alcohol Withdrawal

Cannabis remains one of the most universally abused recreational drugs. Cannabis abuse can have several cardiovascular adverse effects and an overdose can lead to cardiac arrest. Binge alcohol drinking and subsequent withdrawal in the background of cannabis overdose can lead to convulsion and QT prolongation leading to malignant arrhythmia. We report two cases of ventricular fibrillation complicated with seizure precipitated by cannabis overdose and alcohol withdrawal. Such serious clinical presentation complicated with cardiac arrest does not necessarily lead to a fatal outcome if timely medical attention and care are provided. Timely aggressive resuscitative measures combined with intensive care can lead to a successful outcome. Later on, psychiatric counseling and occupational and behavioral therapies can help them to live longer.