Enhanced drug delivery, mechanical properties and antimicrobial activities in poly(lactic acid) nanofiber with mesoporous Fe3O4-COOH nanoparticles

Chao Han,Ning Cai,Vincent Chan,Mingming Liu,Xiaojuan Feng,Faquan Yu

Colloids and Surfaces A: Physicochemical and Engineering Aspects（2018）

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摘要

•Dual sustained drug release system was designed by a facile strategy.•Biocompatible and mesoporous Fe3O4−COOH nanoparticles were synthesized for designing drug carrier.•Improved mechanical performance and sustained drug release behavior were achieved.

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关键词

Sustained drug release,Mechanical properties,Electrospinning,Composite nanofiber,Iron oxide nanoparticles,Poly(lactic acid)

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