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A Polymer-Gel Eye-Phantom For 3d Fluorescent Imaging Of Millimetre Radiation Beams

Leonard H. Luthjens, Tiantian Yao, John M. Warman

POLYMERS(2018)

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摘要
We have filled a 24 mm diameter glass sphere with a transparent polymer-gel that is radio-fluorogenic, i.e., it becomes (permanently) fluorescent when irradiated, with an intensity proportional to the local dose deposited. The gel consists of >99.9% tertiary-butyl acrylate (TBA), pre-polymerized to similar to 15% conversion, and similar to 100 ppm maleimido-pyrene (MPy). Its dimensions and physical properties are close to those of the vitreous body of the human eye. We have irradiated the gel with a 3 mm diameter, 200 kVp X-ray beam with a dose rate of similar to 1 Gy/min. A three-dimensional (3D) (video) view of the beam within the gel has been constructed from tomographic images obtained by scanning the sample through a thin sheet of UV light. To minimize optical artefacts, the cell was immersed in a square tank containing a refractive-index-matching medium. The 20-80% penumbra of the beam was determined to be similar to 0.4 mm. This research was a preparatory investigation of the possibility of using this method to monitor the millimetre diameter proton pencil beams used in ocular radiotherapy.
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关键词
radiotherapy eye-phantom,radio-fluorogenic gel,X-ray beam imaging,3D radiation imaging,polymer gel dosimetry
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