LRG1 is a novel regulator of endothelial activation and is shear dependent: A Potential therapeutic target?

K.T. Pang, C.W. Fhu,M. Ghim, H.M. Tay,H.W. Hou, Q. Lu,Christina M. Warboys,X. Wang,Peter D. Weinberg

CARDIOVASCULAR RESEARCH（2018）

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摘要

Aim: Leucine-rich-alpha-2-glycoprotein-1(LRG1), a novel TGF-β pathway regulator, has altered concentration in serum of patients with autoimmune and inflammatory diseases. This study aims to investigate the role of LRG1 in endothelial activation.

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关键词

endothelial activation,potential therapeutic target,novel regulator

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