Abstract 18610: Preliminary Evaluation of a Wrist Wearable Heart Rate Sensor for the Detection of Undiagnosed Atrial Fibrillation in a Real-World Setting

Introduction: As part of a large digital medicine study investigating the identification of asymptomatic atrial fibrillation (AF) using a continuous single-lead ECG patch, we evaluated the usability and the efficacy of a wrist wearable device for the detection of AF. Hypothesis: A wearable, non-ECG sensor will allow for rhythm monitoring for longer periods of time and therefore potentially provide the evidence to motivate future large studies on photoplethysmography (PPG) based AF detection. Methods: We provided via mail an Amiigo wrist worn PPG device (Wavelet Health) to 237 subjects randomly selected, along with instructions on how to use device and mobile app. Due to battery constraints, the devices collected PPG data for 30 seconds every 20 minutes during day and every 7 minutes by night. On a subset of the available data, the intervals of heart rate data were further analyzed by computing the Shannon entropy on the differences between consecutive RR intervals, and detecting AF event with a threshold ...