Simvastatin and ezetimibe reduce plasma lipoprotein binding to human arterial proteoglycans in gallstone diseased patients

K. Littmann,O. Ahmed,Ulf Gustafsson,Camilla Pramfalk,K. Öörni,Lilian Larsson,Staffan Sahlin,G. Camejo,Paolo Parini,M. Eriksson

ATHEROSCLEROSIS（2018）

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摘要

Aim: Binding to arterial proteoglycans (PG) are an indicator for lipoprotein deposition in the arterial wall. Small dense LDL have higher affinity for PG binding than larger LDL. LDL particles from patients with coronary heart disease also have higher affinity.

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关键词

Cholesterol-lowering

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