Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Recapitulate Clinical Phenotypes in a Multigenerational Family With Early Onset Atrial Fibrillation and Long Qt Syndrome
Circulation(2014)
摘要
Introduction: Early-onset atrial fibrillation (AF) and Long QT Syndrome (LQTS) are associated with gain- and loss-of-function mutations in cardiac potassium channel genes, respectively. Counterintu...
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关键词
Gene mutations,Ion channels,Stem cells,Atrial fibrillation,Genomics
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