Beneficial changes of gut microbiota and metabolism in weaned rats with Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 supplementation

•Supplementation of L-NCFM and B-LBi07 regulate host metabolism and gut microbiota metabolism.•Supplementation of L-NCFM and B-LBi07 increase beneficial bacteria and inhibit harmful bacteria.•Supplementation of L-NCFM and B-LBi07 promote the functional maturation of gut bacterial community.•Key Metabolites are strongly correlated with the gut microbiota composition.