Biotransformation of 4-hydroxyphenylacetonitrile to 4-hydroxyphenylacetic acid using whole cell arylacetonitrilase of Alcaligenes faecalis MTCC 12629

Neerja Thakur,Vijay Kumar,Shikha Thakur,Nikhil Sharma,Sheetal,Tek Chand Bhalla

Process Biochemistry（2018）

引用 12|浏览20

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摘要

•Hyperinduction of nitrilase by inducer feeding approach.•Nitrilase mediated biotransformation of 4-hydroxyphenylacetonitrile.•Bioprocess development for 4-hydroxyphenylacetic acid synthesis.•Fed batch synthesis at 500 ml scale.

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关键词

Nitrilase,Bioprocess,4-Hydroxyphenylacetic acid

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