Prevalence of hepatitis e virus infection in liver donors in spain

Abstract • We conducted a retrospective and cross-sectional study where formalinfixed liver tissue samples from recipients transplanted and donors in the period between 2012 and 2016 were analyzed for HEV analysis by RT-PCR. • HEV RNA was not detected in any of the explant tissue analyzed (n =105), meaning that the prevalence of HEV infection was 0%. • In the liver graft tissue (n = 105), one sample was HEV RNA-positive, thus the prevalence of HEV infection in the liver allografts was 0.95% (95% CI: 0%-5.7%). • Our study reports the prevalence of HEV infection in both liver organ donors and recipients in Spain, suggesting a potential risk of transmission through this route.