1,2-Dihaloalkenes in Metal-Catalyzed Reactions

1,2-Dihaloalkenes readily undergo simultaneous or sequential difunctionalization through transition-metal-catalyzed reactions, which makes them attractive building blocks for complex unsaturated motifs. This review summarizes recent applications of such transformations in C-C and C-heteroatom bond forming processes. The facile synthesis of stereodefined alkene derivatives, as well as aromatic and heteroatomic compounds, from 1,2-dihaloalkenes is thus outlined. 1 Introduction 2 Synthesis of 1,2-Dihaloalkenes 3 C-C Bond Forming Reactions 4 C-Heteroatom Bond Forming Reactions 5 Conclusion