Heat-killed Lactobacillus casei subsp. casei 327 promotes colonic serotonin synthesis in mice

Takashi Hara,Toshihiro Mihara, Mitsuhisa Ishibashi,Toshio Joh

Journal of Functional Foods（2018）

引用 16|浏览6

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摘要

•L. casei subsp. casei 327 (Lc327) is a promising strain for improving defecation.•Heat-killed Lc327 increased colonic serotonin level in mice.•Heat-killed Lc327 enhanced tryptophan hydroxylase 1 expression in mouse colonic epithelium.•Heat-killed Lc327 shortened the transit time of colonic bead expulsion in mice.

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关键词

Heat-killed probiotics,Lactobacillus casei subsp. casei 327,Serotonin,Tryptophan hydroxylase 1,Enterochromaffin cells,Colon transit

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