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Long-Term Effects Of Ezetimibe Plus Statin Combination Vs Double-Dose Statin Therapy On Low-Density Lipoprotein Cholesterol Lowering In Coronary Artery Disease Patients Pre-Treated With Statins; Focus On Proprotein Convertase Subtilisin/Kexin Type 9

Kozo Okada,Noriaki Iwahashi,Tsutomu Endo,Hideo Himeno,Kazuki Fukui,Shunichi Kobayashi,Makoto Shimizu,Yuji Iwasawa,Yukiko Morita,Atsushi Wada,Tomohiko Shigemasa,Yasuyuki Mochida,Tomoaki Shimizu,Reimin Sawada,Kazuaki Uchino,Satoshi Umemura,Kazuo Kimura

Circulation（2012）

Cited 23|Views37
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Abstract
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to hepatic LDL receptor, causing its subsequent degradation. Although statin therapy is known to increase concentrations of P...
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Key words
statins,statin combination,proprotein convertase subtilisin/kexin,long-term,double-dose,low-density,pre-treated
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