Border collies of the genome: domestication of an autonomous retrovirus-like transposon

Current Genetics(2018)

Cited 4|Views9
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Abstract
Retrotransposons often spread rapidly through eukaryotic genomes until they are neutralized by host-mediated silencing mechanisms, reduced by recombination and mutation, and lost or transformed into benevolent entities. But the Ty1 retrotransposon appears to have been domesticated to guard the genome of Saccharomyces cerevisiae .
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Key words
Retrovirus-like transposon, Retrotransposon, Ty1, Mediator, Domestication
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