Characterization of a metagenomic serine metalloprotease and molecular docking studies

Kashif Shamim,Jaya Sharma,Milind Mutnale,Santosh Kumar Dubey,Sajiya Yusuf Mujawar

Process Biochemistry（2018）

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摘要

•Cloning of thermoalkalophilic serine metalloprotease from marine metagenomic library.•Enzyme activity was enhanced by certain bivalent cations and organic solvents.•Protease interacts with gp41 of HIV- 1 and cell adhesion protein of Listeria monocytogenes.

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关键词

Serine,Metalloprotease,Metagenomic library,Expression,Next-generation sequencing,In silico docking

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