The Thyroid Hormone-target Gene Rhes a Novel Crossroad for Neurological and Psychiatric Disorders: New Insights from Animal Models

Francesco Napolitano,Livia D'Angelo,Paolo de Girolamo,Luigi Avallone,Pieter de Lange,Alessandro Usiello

Neuroscience（2018）

引用 17|浏览10

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摘要

•The striatum-enriched protein Rhes is developmentally regulated by thyroid hormone.•Rhes modulates striatal dopamine-dependent transmission.•Rhes influence neurological and psychiatric phenotypes in animal models.

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关键词

DA,DMT1,EGF,FGF,GPCR,GPi,HD,IGF-1,ISH,KO,mHtt,MPTP,MSNs,PCP,PD,PDGF,PPI,PTX,Rhes,STN,TH,TSH,WT

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