Mo1350 NEWLY DEVELOPED TREATMENT SYSTEM USING ENDOSCOPIC ULTRASOUND GUIDED HIGH INTENSITY FORCUSED ULTRASOUND

High-intensity focused ultrasound (HIFU) is a novel minimally invasive modality for ablation of various solid tumors including pancreatic cancer. Currently, the thermal effect of HIFU has been mainly used for tumor treatment. However, over coagulation may suppress effective delivery of anti-tumor drug. Recent studies also found that the mechanical effect of HIFU may help to enhance drug delivery although much higher acoustic intensity is necessary. For current HIFU therapy, large equipment is needed to obtain sufficient acoustic intensity and therefore it is often difficult to achieve an adequate acoustic window by extracorporeal transducer.