Clinical Factors Related to Severity of Dementia: A Retrospective Survey from 50 Geriatric Hospitals in Korea (P1.094)

Neurology(2016)

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摘要
Objective: The results of clinical studies about the severity of dementia patients are limited in Korea. We do this study to suggest information about the severity of dementia and to estimate the outcome of dementia inpatients.Background:We reviewed medical records to investigate clinical factors related to severity of dementia and to inspect the clinical factors related to the progression of dementia severity.Methods:The patients who visited the hospital by first time between March 2012 and February 2014, among the patients with dementia admitted to 50 geriatric hospitals spread all over Korea, formed the analysis cohorts. Retrospective review of medical records was performed.Results: A total of 2965 patients were included during that period. The average duration of illness is 24.61±28.18 months. By the severity of illness, mild cases were 1032 patients (34.81[percnt]), moderate cases 1278 (43.10[percnt]), severe cases 655 (22.09[percnt]), and mean score of MMSE was 14.82±6.24. The severity of dementia is higher in patients with overweight by 3.10 times (p=0.017, 95[percnt]CI[1.38-6.96]), existence of inmate by 5.92 times (p=0.0002, 95[percnt]CI[2.35-14.91]), past history of aphasia symptom by 0.18 times (p=0.0004, 95[percnt]CI[0.07-0.47]). Among the clinical factors related to the progression of dementia severity, female patients showed longer duration of illness by 2.89 times compared with average, by the results of univariate analysis of 120 severe dementia patients clinical data.Conclusion: Among the clinical factors related to severity of dementia in an inpatients of 50 geriatric hospital in Korea, severity of dementia is higher in patients with overweight, existence of inmate and past history of aphasia symptom. The progression speed of dementia is suggested to be slow in female, regarding longer duration of illness in severe dementia patients than male. Disclosure: Dr. Lee has nothing to disclose. Dr. Hwang has nothing to disclose. Dr. Suk has nothing to disclose. Dr. Minn has nothing to disclose. Dr. Song has nothing to disclose. Dr. Park has nothing to disclose. Dr. Koh has nothing to disclose.
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