小细胞肺癌合并抗γ-氨基丁酸B受体脑炎1例报道
Cancer Research on Prevention and Treatment（2018）
Abstract
0引言
小细胞肺癌(small cell lung cancer,SCLC)占肺癌比例约15％,其特点为高侵袭性、生长迅猛、早期转移、对放化疗较为敏感、但预后差[1].小细胞肺癌相关边缘性脑炎(limbic encephalitis,LE)最常见的是抗γ-氨基丁酸B(GABA-B)受体脑炎.抗GABA-B受体脑炎是一种非常少见的自身免疫性脑炎,国内外报道的病例不到百例.在报道的抗GABA-B受体脑炎病例中,50％～60％患者合并小细胞肺癌[2],而小细胞肺癌合并抗GABA-B受体脑炎确诊的病例更是罕见.现将1例确诊为小细胞肺癌合并抗GABA-B受体脑炎的病例报道如下.
MoreKey words
gabab receptor encephalitis,small cell lung cancer,antibodies,lung cancer
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