Bioassay-guided purification of Lippia citriodora polyphenols with AMPK modulatory activity

María de la Luz Cádiz-Gurrea,Mariló Olivares-Vicente,María Herranz-López,David Arráez-Román,Salvador Fernández-Arroyo,Vicente Micol,Antonio Segura-Carretero

Journal of Functional Foods（2018）

引用 21|浏览15

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摘要

•A total of 29 compounds were tentatively identified by HPLC-ESI-TOF-MS.•Semi-preparative HPLC provides purified compounds with AMPK modulation activity.•Fractions with pure verbascoside showed the highest activating capacity.•Lippia citriodora is a potential source for the obtainment of bioactive compounds for food industry.

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关键词

Lippia citriodora,Purification,HPLC,Phenylpropanoids,AMPK

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