Yeastsci: A Web Tool Integrating Zinc Cluster Protein Information Of Saccharomyces And Candida

PROCEEDINGS OF 2018 6TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND COMPUTATIONAL BIOLOGY (ICBCB 2018)(2018)

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摘要
The zinc cluster proteins act as transcriptional regulators only found in fungi. The human pathogen Candida, zinc cluster transcription factors that involve in controlling the expression of virulence genes and play roles in multidrug resistance. The yeast Saccharomyces cerevisiae has a close relationship to Candida as it has genes encoded with zinc cluster proteins. Previously, the researchers need to search from the publications manually or from the Candida Genome Database and Saccharomyces Genome Database separately. This is a time-consuming process. In this paper, we have developed the web tool accessible online called Yeast Saccharomyces and Candida Integrated (YeastSCI). The tool provides the integration information of Saccharomyces and Candida from popular databases. Furthermore, a hybrid cacheable technique is proposed to make the tool self-updatable and provide a real-time information efficiently.
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关键词
Candida, Saccharomyces, Web tool, Zinc cluster regulators
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