Su2024 - Patterns of use and Durability of Initial and Subsequent Biological Agents in a Large Pediatric Inflammatory Bowel Disease Observational Cohort

Gastroenterology(2018)

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摘要
remaining colectomy-free at 3, 6, 12, 24 and 36 months was 97%, 94%, 86%, 80% and 70%.14 hospitalizations occurred in 8 patients, and 5 serious infections occurred in 5 patients.Concomitant immunomodulator therapy did not appear to improve outcomes.Conclusions: Durable rates of steroid-free remission were observed in pediatric patients with UC on ADA in routine practice.Of patients followed for 24 months, 97% of patients remained on ADA and approximately 70% of patients were in steroid-free clinical remission.80% of patients remained colectomy-free for 24 months.Table percentages are calculated based on non-missing values Su2023
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subsequent biological agents
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