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In Vivo Screening Identifies Esr1 As A Clinically Relevant Target For Radiosensitization In Hnscc

Aakash Sheth,David Molkentine,Kathleen Bridges, Kumar,Liangpeng Yang,Tongxin Xie, Mitchell Fredrick,Jeffrey Myers,Raymond Meyn,Curtis Pickering,Heath Skinner

International Journal of Radiation Oncology*Biology*Physics（2018）

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Abstract
Targeting of Estrogen Receptor 1 (ESR1) has been part of the mainstay of treatment for estrogen receptor-positive (ER+) breast cancers. However, the significance of ESR1 in other malignancies is unclear.
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vivo screening identifies esr1,radiosensitization,clinically relevant target
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