Potential protective effect of Trans-10-hydroxy-2-decenoic acid on the inflammation induced by Lipoteichoic acid
Journal of Functional Foods(2018)
摘要
•LTA is a virulence factor which elicits severe inflammatory response in immune cells.•10-HDA alleviated LTA-induced pulmonary damage in vivo.•10-HDA inhibited the release of IL-6, TNF-α and NO in LTA-induced cells.•10-HDA attenuated LTA induced inflammation through MAPK signaling pathways.
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关键词
Royal jelly,10-HDA,Lipoteichoic acid,Inflammation mediators,Acute lung injury
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